Comparison of radiation-induced DNA damage modeling approaches for proton therapy treatment planning

ทรัพยากร : หนังสือ
คะแนน :
ผู้แต่ง : Sanhanat Chaibura
วันที่เผยแพร่ : 02/11/2026
สำนักพิมพ์ : Chulabhorn Royal Academy
หมวดหมู่ : medicine
จำนวนหน้า : 87p.ill.;21.5cm.
Description :

Proton beam therapy (PBT) offers advantages over conventional photon therapy due to its precise dose delivery and potential for sparing healthy tissue. However, the variable relative biological effectiveness (RBE) of protons, particularly at the distal edge of the spread-out Bragg peak, presents challenges for accurate treatment planning. This study investigates and compares different approaches for modeling radiation-induced DNA damage, specifically focusing on single-strand breaks (SSBs) and double-strand breaks (DSB), with the aim of improving biological effect prediction in PBT treatment planning.

Details :
245 - Title statement
100 - Main entry--personal name
300 - Physical description
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